ANALYTICAL TOOLS FOR THE CHARACTERIZATION OF DEAMIDATION IN MONOCLONAL ANTIBODIES


Plant traits and environment: floating leaf blade production and turnover of Nymphoides peltata (S.G. Gmel.) O. Kuntze (Menyanthaceae)

Background Nymphaeid macrophytes, rooting in the sediment of water bodies and characterized by floating leaves, play an important role in wetland ecosystems.The present research deals with the effects of limited space, limited nutrient availability, water temperature and an unexpected inundation on the production, turnover and plasticity of floatin

read more

Achievement of Unidirectional Aluminum Tin Oxide/UV-Curable Polymer Hybrid Film via UV Nanoimprinting Lithography for Uniform Liquid Crystal Alignment

A uniform unidirectional nanostructure composed of aluminum tin oxide and ultraviolet (UV)-curable polymer is introduced herein.The nanostructure was produced by UV-nanoimprint lithography (UV-NIL), and the fabricated hybrid film was used as a uniform liquid crystal (LC) alignment layer.Atomic force microscopy and line profile analysis were perform

read more

P2X3 receptors mediate visceral hypersensitivity during acute chemically-induced colitis and in the post-inflammatory phase via different mechanisms of sensitization.

ObjectivesExperiments using P2X3 knock-out mice or more general P2X receptor antagonists suggest that P2X3 receptors contribute to visceral hypersensitivity.We aimed to investigate the effect of the selective P2X3 antagonist A-317491 Toys on visceral sensitivity under physiological conditions, during acute colitis and in the post-inflammatory phase

read more

Prognostic impact of reduced HER2 protein expression in post-neoadjuvant therapy resection specimens: A single institution experience and review of the literature

Background: Retesting for Human epidermal growth factor receptor-2 (HER2) in post-neoadjuvant therapy resection is variable, and data is conflicting regarding Necklaces the prognostic significance of changes in HER2 expression pre and post therapy.Methods: We identified 104 patients with localized HER2 IHC 3+ breast cancer who received neoadjuvant

read more